The CVS on City Avenue was robbed early Tuesday morning, Lower Merion police said.
Two black men standing between 5 feet 4 inches and 5 feet 11 inches tall entered the 24-hour store about 4:55 a.m., announcing a robbery and ordering all three employees into a back room, police said.
One employee opened a safe and removed cash as one of the robbers displayed a handgun.
There were no reports of injuries.
It was the first robbery reported at the pharmacy since two men made off with an undetermined amount of cash .
Anyone with information about the robbers may call police at 610-649-1000.